Search results for "Trichloroacetic acid"

showing 10 items of 14 documents

IGF-I, IgA, and IgG responses to bovine colostrum supplementation during training.

2002

This study examined the effect of bovine colostrum (Dynamic colostrum) supplementation on blood and saliva variables ( study 1) and the absorption of orally administered human recombinant insulin-like growth factor (IGF)-I (rhIGF-I) labeled with 123I (123I-rhIGF-I) ( study 2). In study 1, adult male and female athletes were randomly assigned in a double-blind fashion to either an experimental (Dynamic; n = 19) or a control (Placebo; n = 11) group. The former consumed daily 20 g of Dynamic supplement, and the latter 20 g of maltodextrin during a 2-wk training period. After bovine colostrum supplementation, significant increases were noticed in serum IGF-I ( P < 0.01) and saliva IgA ( P &…

AdultElectrophoresisMaleSalivamedicine.medical_specialtyPhysiologyCausticsAnimal originlaw.inventionReceptor IGF Type 1Iodine RadioisotopesDouble-Blind MethodlawPhysiology (medical)Internal medicinemedicineAnimalsHumansInsulin-Like Growth Factor ITrichloroacetic AcidSalivabusiness.industryColostrumImmunoglobulin AEndocrinologyNutrition AssessmentPhysical performancePhysical FitnessImmunoglobulin GDietary SupplementsRecombinant DNAColostrumCattleFemalebusinessJournal of applied physiology (Bethesda, Md. : 1985)
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Chlorinated acetic and propionic acids in pine needles from industrial areas

1998

Abstract Concentrations of chlorinated acetic and propionic acids in pine needles from the surroundings of a pulp and paper mill and a metal reclamation plant were measured. Different ways of extraction and chromatographic separation were tried. Ultrasonic extraction with water of the powdered needles was found to be efficient. The acids were analysed as their pentafluorobenzyl esters with GC-ECD. The ECD sensitivity of the pentafluorobenzyl derivatives was good. The detection limit was below 1 ng/g for the chlorinated acetic and propionic acids. The concentrations of dichloroacetic acid and 2,2-dichloropropionic acid in fresh needles were on the 0–4 ng/g level. Monochloroacetic acid, 2-chl…

Detection limitEnvironmental EngineeringChromatographyChemistrybusiness.industryHealth Toxicology and MutagenesisPulp (paper)Public Health Environmental and Occupational HealthMONOCHLOROACETIC ACIDDichloroacetic acidPaper millGeneral MedicineGeneral Chemistryengineering.materialPollutionChromatographic separationchemistry.chemical_compoundengineeringEnvironmental ChemistryOrganic chemistryTrichloroacetic acidbusinessChemosphere
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The development and validation of a rapid method for the determination of antimicrobial agent residues in milk and meat using ultra performance liqui…

2014

Abstract A new multi-class method has been developed for the identification and quantification of the residues of 26 antibiotics from different classes (sulfonamides, macrolides, tetracyclines, penicillins, and quinolones) in milk and meat by ultra performance liquid chromatography coupled to hybrid quadrupole – high resolution Orbitrap mass spectrometry (UPLC–qOrbitrap). The sample preparation included extraction of two analytical portions with acetonitrile and 5% trichloroacetic acid, respectively, followed by centrifugation and filtration. The method was validated over three days at 50% of MRL (maximum residue limit) set in the European Union. Experiments on spiked meat and milk samples …

MeatMaximum Residue LimitClinical BiochemistryPharmaceutical ScienceMass spectrometryOrbitrapHigh-performance liquid chromatographyMass SpectrometryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundAnti-Infective AgentslawDrug DiscoveryAnimalsmedia_common.cataloged_instanceSample preparationTrichloroacetic acidEuropean unionChromatography High Pressure LiquidSpectroscopymedia_commonChromatographyExtraction (chemistry)Drug ResiduesMilkchemistryJournal of Pharmaceutical and Biomedical Analysis
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Translocation versus cyclisation in radicals derived from N-3-alkenyl trichloroacetamides

2011

Under radical reaction conditions, two different and competitive reaction pathways were observed for N-(alpha-methylbenzyl)trichloroacetamides with a N-3-cyclohexenyl substituent: 1,4-hydrogen translocation and radical addition to a double bond. However, for radicals with an acyclic alkenyl side chain, the direct cyclisation process was exclusively observed. The dichotomy between translocation and direct radical cyclisation in these substrates has been theoretically studied using density functional theory (DFT) methods at the B3LYP/6-31G** computational level.

Models MolecularFree RadicalsDouble bondStereochemistryRadicalSubstituentChromosomal translocationAlkenesBiochemistryPolarizable continuum modelchemistry.chemical_compoundQUIMICA ORGANICAAcetamidesQUIMICA ANALITICASide chainMoleculeTOOLChloroacetatesTrichloroacetic AcidPhysical and Theoretical ChemistryAMIDESchemistry.chemical_classificationMolecular StructureChemistryOrganic ChemistryCOPPER-COMPLEXESCyclizationPOLARIZABLE CONTINUUM MODELDensity functional theory
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Die Beziehung zwischen der Guanethidin-Konzentration im Rattenherzen und dem Noradrenalingehalt

1962

Guanethidine was intravenously injected into rats and was subsequently determined in the hearts by extracting the tissue with trichloroacetic acid, purifying the extracts on cation exchange columns and by paper chromatography, and coupling the guanethidine with ninhydrin in alkaline solution before fluorimetric estimation. The concentration in the heart reached a maximum of 9 μg/g within 15 min of injecting 15 mg/kg, and was still 6.2 and 5.7 μg/g after 1 and 3 hours, respectively. Guanethidine caused a decrease of the heart noradrenaline concentration, measured fluorimetrically, by 56% in 3 hours and by 93% in 14 hours. The adrenaline concentration was likewise decreased. A metabolite with…

PharmacologyChromatographyMetaboliteGeneral MedicineRat heartUrineNorepinephrine (medication)Paper chromatographychemistry.chemical_compoundchemistryNinhydrinmedicineTrichloroacetic acidGuanethidinemedicine.drugNaunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie
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Isolation and purification of plasmids from Bacteroides fragilis using rubidium trichloroacetate density gradient centrifugation.

1983

A rapid and easy final purification method is described for the isolation of plasmids from B. fragilis. Using RbTCA density gradient centrifugation in an airfuge ultracentrifuge ccc plasmid DNA can be separated from RNA, residual chromosomal DNA, linear and oc plasmid DNA. Pure ccc plasmid DNA is obtained from cultures of between 1 ml and 2 l in less than one day.

Plasmid preparationDifferential centrifugationDNA BacterialRNAchemistry.chemical_elementBiologyIsolation (microbiology)RubidiumMolecular biologyRubidiumBacteroides fragilisPlasmidchemistryGeneticsCentrifugation Density GradientUltracentrifugePurification methodsTrichloroacetic AcidMolecular BiologyPlasmidsMoleculargeneral genetics : MGG
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CCDC 1537659: Experimental Crystal Structure Determination

2017

Related Article: Georges Mouchaham, Nans Roques, Walid Khodja, Carine Duhayon, Yannick Coppel, Stéphane Brandès, Tamás Fodor, Michel Meyer and Jean-Pascal Sutter|2017|Chem.-Eur.J.|23|11818|doi:10.1002/chem.201701732

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters44'-((2-(((pyridin-1-ium-4-yl)oxy)methyl)-2-(((pyridin-4-yl)oxy)methyl)propane-13-diyl)bis(oxy))di(pyridin-1-ium) tris(oxalato)-aluminium trichloroacetic acid hydrateExperimental 3D Coordinates
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A deep insight into the mechanism of the acid-catalyzed rearrangement of the Z-phenylhydrazone of 5-amino-3-benzoyl-1,2,4-oxadiazole in a non-polar s…

2010

The conversion of the Z-phenylhydrazone of 5-amino-3-benzoyl-1,2,4-oxadiazole (1a) into the relevant 1,2,3-triazole (2a) has been quantitatively studied in toluene in the presence of several halogenoacetic acids (HAAs, 3a–h). Again, the occurrence of two reaction pathways has been pointed out: they require one or two moles of acid, respectively, thus repeating the situation previously observed in the presence of trichloroacetic acid. The observed rate constant ratios (kIII/kII) are only slightly affected by the nature of the acid used. To gain a deeper insight into the action of the acids used we have measured the association constants of the HAAs (3a–h) with 4-nitroaniline (4) in toluene. …

StereochemistryOrganic ChemistryOxadiazoleSettore CHIM/06 - Chimica OrganicaTolueneMedicinal chemistrySolventchemistry.chemical_compoundAcid catalysisReaction rate constantchemistryAcid catalyzedMoleAcid catalysis azoles mononuclear rearrangement of heterocycles ring to ring interconversionPhysical and Theoretical ChemistryTrichloroacetic acidJournal of Physical Organic Chemistry
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Acid- and Base-Catalysis in the Mononuclear Rearrangement of Some (Z)-arylhydrazones of 5-Amino-3-benzoyl-1,2,4-oxadiazole in Toluene: Effect of Subs…

2011

The reaction rates for the rearrangement of eleven (Z)-arylhydrazones of 5-amino-3-benzoyl-1,2,4-oxadiazole 3a-k into the relevant (2-aryl-5-phenyl-2H-1, 2,3-triazol-4-yl)ureas 4a-k in the presence of trichloroacetic acid or of piperidine have been determined in toluene at 313.1 K. The results have been related to the effect of the aryl substituent by using Hammett and/or Ingold-Yukawa-Tsuno correlations and have been compared with those previously collected in a protic polar solvent (dioxane/water) as well as with those on the analogous rearrangement of the corresponding (Z)-arylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazole 1a-k in benzene. Some light can thus be shed on the general di…

SubstituentOxadiazoleAlkaliesMedicinal chemistryCatalysisDioxanesStructure-Activity RelationshipAcid catalysischemistry.chemical_compoundPiperidinesUreaOrganic chemistryAminesTrichloroacetic AcidBenzeneBiological ProductsOxadiazolesMolecular StructureArylMRH acid- and base-catalysis kinetic measurementsOrganic ChemistryHydrazonesTemperatureWaterSettore CHIM/06 - Chimica OrganicaTolueneSolventKineticschemistryMononuclear rearrangements of heterocycles; (Z)-Arylhydrazones; acid catalysis; base catalysis.PiperidineHydrophobic and Hydrophilic InteractionsToluene
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Total Synthesis of the Glycopeptide Recognition Domain of the P-Selectin Glycoprotein Ligand 1

2008

ThreonineGlycosylationGlycosylationOligosaccharidesCatalysischemistry.chemical_compoundSolid-phase synthesisProtein structureAcetamidesHumansChloroacetatesTrichloroacetic AcidBinding siteThreonineAntigens Viral TumorSialyl Lewis X AntigenBinding SitesMembrane GlycoproteinsGlycopeptidesTotal synthesisGeneral ChemistryGlycopeptideProtein Structure TertiaryP-SelectinchemistryBiochemistryP-selectin glycoprotein ligand-1Angewandte Chemie International Edition
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